The challenges of caring for children with complex health needs, such as intellectual disability (ID) and autism spectrum disorder (ASD), are multiple and experienced by both caregivers and health professionals.Fragile X syndrome (FXS) is the most common single gene cause of ID and ASD, and provides a pertinent model to understand these complexitie
Highly compressible 3-D hierarchical porous carbon nanotube/metal organic framework/polyaniline hybrid sponges supercapacitors
Optimization of the transport behaviors of ions and electrons is the key for the property improvement of supercapacitor, which are essentially controlled by the design of hierarchical porous structure and electrical conductive backbone, from nanoscale to microscale, respectively.However, such design requirements are 03.2150.400 very difficult to be
Consumer preferences for parcel delivery methods
In the Netherlands, as in many other densely populated countries, home delivery is the dominant way of delivering online ordered parcels.This is mainly because big retail companies offer this delivery option for free.Due to the terracotta charger expansion of e-commerce, home delivery that typically makes use of diesel vans puts increasing pressure
SFTSV nucleoprotein mediates DNA sensor cGAS degradation to suppress cGAS-dependent antiviral responses
ABSTRACT Cyclic GMP-AMP synthase (cGAS) is an important DNA pattern recognition receptor that senses double-stranded DNA derived from invading pathogens or self DNA in cytoplasm, leading to an antiviral interferon response.A tick-borne Bunyavirus, severe fever with thrombocytopenia syndrome virus (SFTSV), is an RNA virus that causes a severe emergi